diff --git a/clause/expression.go b/clause/expression.go
index b30c46b0..3844d66b 100644
--- a/clause/expression.go
+++ b/clause/expression.go
@@ -203,7 +203,7 @@ type Eq struct {
 func (eq Eq) Build(builder Builder) {
 	builder.WriteQuoted(eq.Column)
 
-	if eq.Value == nil {
+	if eqNil(eq.Value) {
 		builder.WriteString(" IS NULL")
 	} else {
 		builder.WriteString(" = ")
@@ -221,7 +221,7 @@ type Neq Eq
 func (neq Neq) Build(builder Builder) {
 	builder.WriteQuoted(neq.Column)
 
-	if neq.Value == nil {
+	if eqNil(neq.Value) {
 		builder.WriteString(" IS NOT NULL")
 	} else {
 		builder.WriteString(" <> ")
@@ -299,3 +299,12 @@ func (like Like) NegationBuild(builder Builder) {
 	builder.WriteString(" NOT LIKE ")
 	builder.AddVar(builder, like.Value)
 }
+
+func eqNil(value interface{}) bool {
+	return value == nil || eqNilReflect(value)
+}
+
+func eqNilReflect(value interface{}) bool {
+	reflectValue := reflect.ValueOf(value)
+	return reflectValue.Kind() == reflect.Ptr && reflectValue.IsNil()
+}
diff --git a/clause/expression_test.go b/clause/expression_test.go
index 83082486..9e3d7bad 100644
--- a/clause/expression_test.go
+++ b/clause/expression_test.go
@@ -101,3 +101,52 @@ func TestNamedExpr(t *testing.T) {
 		})
 	}
 }
+
+func TestExpression(t *testing.T) {
+	column := "column-name"
+	results := []struct {
+		Expressions    []clause.Expression
+		Result string
+	}{{
+		Expressions: []clause.Expression{
+			clause.Eq{Column: column, Value: "column-value"},
+		},
+		Result: "`column-name` = ?",
+	},{
+		Expressions: []clause.Expression{
+			clause.Eq{Column: column, Value: nil},
+			clause.Eq{Column: column, Value: (*string)(nil)},
+			clause.Eq{Column: column, Value: (*int)(nil)},
+			clause.Eq{Column: column, Value: (*bool)(nil)},
+			clause.Eq{Column: column, Value: (interface{})(nil)},
+		},
+		Result: "`column-name` IS NULL",
+	},{
+		Expressions: []clause.Expression{
+			clause.Neq{Column: column, Value: "column-value"},
+		},
+		Result: "`column-name` <> ?",
+	},{
+		Expressions: []clause.Expression{
+			clause.Neq{Column: column, Value: nil},
+			clause.Neq{Column: column, Value: (*string)(nil)},
+			clause.Neq{Column: column, Value: (*int)(nil)},
+			clause.Neq{Column: column, Value: (*bool)(nil)},
+			clause.Neq{Column: column, Value: (interface{})(nil)},
+		},
+		Result: "`column-name` IS NOT NULL",
+	}}
+
+	for idx, result := range results {
+		for idy, expression := range result.Expressions {
+			t.Run(fmt.Sprintf("case #%v.%v", idx, idy), func(t *testing.T) {
+				user, _ := schema.Parse(&tests.User{}, &sync.Map{}, db.NamingStrategy)
+				stmt := &gorm.Statement{DB: db, Table: user.Table, Schema: user, Clauses: map[string]clause.Clause{}}
+				expression.Build(stmt)
+				if stmt.SQL.String() != result.Result {
+					t.Errorf("generated SQL is not equal, expects %v, but got %v", result.Result, stmt.SQL.String())
+				}
+			})
+		}
+	}
+}